yvaM [2019-06-19 10:50:40]

similar to hydrolase

locus: BSU33640

pI: 8.99

mw: 29.43 kDa

protein length: 256 aa

gene length: 771 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]
• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

Gene

Coordinates: 3,455,472 3,456,242

The protein

Protein family

• AB hydrolase superfamily (according to Swiss-Prot)

Paralogous protein(s)

• [protein|322BE299860795A70EFA78B8E2614CCCC1CE7C87|YdjP]:

Structure

• [PDB|5EGN] (26% identity)

Expression and Regulation

Operons

• genes: [gene|AD4702CC69AC7D5FF391F14176881D582DD1C68A|yvaM]
  description: (according to [http://dbtbs.hgc.jp/COG/prom/yvaM.html DBTBS]) null

  regulatory mechanism

  • [protein|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|RghR]: repression, [Pubmed|16553878], in [regulon|972401B6AF56EC67FE6F1C3FEA9E2A9FC77C7672|RghR regulon]

  regulation

  • repressed by [protein|search|RghR] [Pubmed|16553878]

Biological materials

Mutant

• MGNA-A447 (yvaM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/447 NBRP B. subtilis, Japan]
• BKE33640 ([gene|AD4702CC69AC7D5FF391F14176881D582DD1C68A|yvaM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGCTTTTCTCCTTTGAC, downstream forward: _UP4_TAGGAATAGAAAACGCTTGG
• BKK33640 ([gene|AD4702CC69AC7D5FF391F14176881D582DD1C68A|yvaM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGCTTTTCTCCTTTGAC, downstream forward: _UP4_TAGGAATAGAAAACGCTTGG

References

• 16553878